Celery seeds found to manage cholesterol levels

A team of researchers from India found that celery seeds (Apium graveolens) significantly improves cholesterol levels and prevents tumor growth. This finding, which was recently published in the Journal of Dietary Supplements, was based on the results of in vivo experiments.

• Previous studies have shown that celery seeds contain coumarin derivatives, namely seselin, methoxsalen, and 3H-isobenzofuran-1-one. Although the structures of these bioactive compounds have already been identified, there are limited studies that look at its potential therapeutic applications.
• In this study, the researchers induced hyperlipidemia in albino rats through the administration of 440 mg/kg body weight of Triton WR 1339. After 24 hours, the animal models were given ethanolic extracts and phytoconstituents of celery at a dosage of 50 mg/kg body weight.
• The team also evaluated potential antitumor effects in hybrid mice of C57BL and Swiss albino strains that were given 50 mg/kg body weight of the experimental treatments for 10 days prior to injection of melanoma tumor cells.
• Results showed that the extracts and compounds from celery significantly reduced total cholesterol, triglycerides, and bad cholesterol levels while the good cholesterol levels increased. Additionally, pretreatment effectively delayed tumor growth.

From these results, the researchers concluded that compounds in celery seeds have potent antihyperlipidemic and antitumor effects.

For more articles about the different health benefits of celery, visit Food.news.

Journal Reference:

Iyer D, Patil UK. ASSESSMENT OF ANTIHYPERLIPIDEMIC AND ANTITUMOR EFFECT OF ISOLATED ACTIVE PHYTOCONSTITUENTS FROM APIUM GRAVEOLENS L. THROUGH BIOASSAY-GUIDED PROCEDURES. Journal of Dietary Supplements. 6 April 2018. DOI: 10.1080/19390211.2018.1448921